No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
|
1. Apply sex-specific ruleonly males |
- |
2. Check conditionsNone |
|
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
- |
4. Check minimum number of eventsNone |
- |
5. Include endpointsNone |
- |
6. Filter based on genotype QC (FinnGen only)None |
- |
Control definitions (FinnGen only)
Control exclude
C3_CANCER, C3_CANCER_WIDE
Extra metadata
First used in FinnGen datafreeze
DF9
Similar endpoints
↥List of similar endpoints to
Seminoma of testis
based on the number of shared cases.
Similar with more cases:
- Seminoma of testis
- Malignant neoplasm, wide definition for exclusion
- Malignant neoplasm, wide definition for exclusion
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥FinnGen case counts by registry codes:
No upset plot: script not run.
No upset table: script not run.
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2654 | - | 2654 |
| Only index persons | 2360 | - | 2360 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | - | 0.07 |
| Only index persons | 0.09 | - | 0.09 |
| Median age at first event (years) | |||
| Whole population | - | - | 36.58 |
| Only index persons | - | - | 36.01 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 311 | - | 311 |
| Unadjusted period prevalence (%) | 0.16 | - | 0.16 |
| Median age at first event (years) | 38.14 | - | 38.14 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint C3_TESTIS_SEMINOMA_EXALLC and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| C3_TESTIS_SEMINOMA_EXALLC | 1.585 [1.27, 1.97] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 136 out of 1812 males with C3_TESTIS_SEMINOMA_EXALLC died.
Mortality risk
Mortality risk for people of age
years, who have C3_TESTIS_SEMINOMA_EXALLC.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.248% |
| 5 | No data | 1.668% |
| 10 | No data | 4.242% |
| 15 | No data | 8.038% |
| 20 | No data | 13.348% |
Relationships between endpoints
↥Index endpoint: C3_TESTIS_SEMINOMA_EXALLC – Seminoma of testis
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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