hemangioma: A benign vascular lesion characterized by the formation of capillary-sized or cavernous vascular channels.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2960 |
4. Check minimum number of eventsNone |
2960 |
5. Include endpointsNone |
2960 |
6. Filter based on genotype QC (FinnGen only) |
2846 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D18
Name in latin
Haemangioma (quovis loco)
Similar endpoints
↥List of similar endpoints to
Haemangioma, any site
based on the number of shared cases.
Similar with more cases:
- Haemangioma, any site
- Haemangioma and lymphangioma, any site
- Haemangioma and lymphangioma, any site
- Benign neoplasms
- Benign neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 28407 | 17050 | 11242 |
| Only index persons | 23788 | 14342 | 9446 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.42 | 0.49 | 0.31 |
| Only index persons | 0.46 | 0.53 | 0.36 |
| Median age at first event (years) | |||
| Whole population | 39.63 | 38.87 | 40.66 |
| Only index persons | 43.95 | 43.68 | 44.37 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2846 | 1833 | 1013 |
| Unadjusted period prevalence (%) | 0.64 | 0.72 | 0.51 |
| Median age at first event (years) | 52.20 | 49.72 | 56.68 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_HEMANGIOMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_HEMANGIOMA | 0.895 [0.79, 1.01] | 0.068 |
| Birth year | 0.995 [0.99, 1.0] | 0.296 |
During the follow-up period (1.1.1998 — 31.12.2019), 908 out of 12925 females with CD2_BENIGN_HEMANGIOMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_HEMANGIOMA | 1.118 [0.99, 1.26] | 0.063 |
| Birth year | 0.988 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 1068 out of 8426 males with CD2_BENIGN_HEMANGIOMA died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_HEMANGIOMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.073% | 0.267% |
| 5 | 0.493% | 1.405% |
| 10 | 1.323% | 3.493% |
| 15 | 2.585% | 6.38% |
| 20 | 4.613% | 11.073% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_HEMANGIOMA – Haemangioma, any site
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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