No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
4228 |
4. Check minimum number of eventsNone |
4228 |
5. Include endpointsNone |
4228 |
6. Filter based on genotype QC (FinnGen only) |
4066 |
Control definitions (FinnGen only)
Control exclude
H7_CHOROIDRETINA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H30-H36
Name in latin
Occlusiones vasculares retinae
Similar endpoints
↥List of similar endpoints to
Retinal vascular occlusion
based on the number of shared cases.
Similar with more cases:
- Retinal detachments and breaks
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 37188 | 18641 | 18366 |
| Only index persons | 34152 | 17322 | 16830 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.52 | 0.53 | 0.51 |
| Only index persons | 0.64 | 0.64 | 0.64 |
| Median age at first event (years) | |||
| Whole population | 72.34 | 74.37 | 70.25 |
| Only index persons | 71.86 | 73.87 | 69.79 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4066 | 1816 | 2250 |
| Unadjusted period prevalence (%) | 0.94 | 0.71 | 1.13 |
| Median age at first event (years) | 69.71 | 69.09 | 70.21 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint H7_RETIVASCOCCLUSION and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETIVASCOCCLUSION | 1.174 [1.08, 1.28] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.142 |
During the follow-up period (1.1.1998 — 31.12.2019), 5754 out of 16475 females with H7_RETIVASCOCCLUSION died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_RETIVASCOCCLUSION | 1.288 [1.17, 1.41] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 5940 out of 16228 males with H7_RETIVASCOCCLUSION died.
Mortality risk
Mortality risk for people of age
years, who have H7_RETIVASCOCCLUSION.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.074% | 0.199% |
| 5 | 0.61% | 1.392% |
| 10 | 1.777% | 3.547% |
| 15 | 3.236% | 6.767% |
| 20 | 5.594% | 11.494% |
Relationships between endpoints
↥Index endpoint: H7_RETIVASCOCCLUSION – Retinal vascular occlusion
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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