No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
400 |
4. Check minimum number of eventsNone |
400 |
5. Include endpointsNone |
400 |
6. Filter based on genotype QC (FinnGen only) |
389 |
Control definitions (FinnGen only)
Control exclude
H7_SCLERACORNEA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H15
Name in latin
Scleritis
Similar endpoints
↥List of similar endpoints to
Scleritis
based on the number of shared cases.
Similar with more cases:
- Scleritis and episcleritis
- Disorders of sclera, cornea, iris and ciliary body
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2446 | 1435 | 995 |
| Only index persons | 2329 | 1379 | 950 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.04 | 0.04 | 0.03 |
| Only index persons | 0.04 | 0.05 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 51.11 | 53.37 | 48.04 |
| Only index persons | 50.92 | 53.12 | 47.73 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 389 | 266 | 123 |
| Unadjusted period prevalence (%) | 0.09 | 0.10 | 0.06 |
| Median age at first event (years) | 52.13 | 51.41 | 53.69 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint H7_SCLERITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_SCLERITIS | 1.084 [0.86, 1.37] | 0.504 |
| Birth year | 1.001 [0.99, 1.01] | 0.834 |
During the follow-up period (1.1.1998 — 31.12.2019), 104 out of 1178 females with H7_SCLERITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_SCLERITIS | 1.021 [0.79, 1.31] | 0.872 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 90 out of 823 males with H7_SCLERITIS died.
Mortality risk
Mortality risk for people of age
years, who have H7_SCLERITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.093% | 0.155% |
| 5 | 0.755% | 1.052% |
| 10 | 1.801% | 2.761% |
| 15 | 3.691% | 5.513% |
| 20 | 6.633% | 9.676% |
Relationships between endpoints
↥Index endpoint: H7_SCLERITIS – Scleritis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data