No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2504 |
4. Check minimum number of eventsNone |
2504 |
5. Include endpointsNone |
2504 |
6. Filter based on genotype QC (FinnGen only) |
2416 |
Control definitions (FinnGen only)
Control exclude
J10_PLEURA
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J90-J94
Name in latin
Pneumothorax
Similar endpoints
↥List of similar endpoints to
Pneumothorax
based on the number of shared cases.
Similar with more cases:
- Other diseases of pleura
- Diseases of the respiratory system
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 22531 | 5868 | 16399 |
| Only index persons | 17810 | 4882 | 12928 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.38 | 0.17 | 0.46 |
| Only index persons | 0.41 | 0.18 | 0.49 |
| Median age at first event (years) | |||
| Whole population | 50.37 | 56.14 | 48.09 |
| Only index persons | 43.39 | 52.37 | 40.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2416 | 689 | 1727 |
| Unadjusted period prevalence (%) | 0.70 | 0.27 | 0.87 |
| Median age at first event (years) | 57.97 | 51.11 | 60.71 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint J10_PNEUMOTHORAX and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_PNEUMOTHORAX | 3.635 [3.02, 4.38] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.272 |
During the follow-up period (1.1.1998 — 31.12.2019), 1318 out of 3535 females with J10_PNEUMOTHORAX died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_PNEUMOTHORAX | 3.073 [2.67, 3.54] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 3115 out of 8847 males with J10_PNEUMOTHORAX died.
Mortality risk
Mortality risk for people of age
years, who have J10_PNEUMOTHORAX.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.378% | 0.728% |
| 5 | 2.178% | 3.226% |
| 10 | 5.309% | 8.486% |
| 15 | 9.927% | 15.785% |
| 20 | 16.779% | 25.869% |
Relationships between endpoints
↥Index endpoint: J10_PNEUMOTHORAX – Pneumothorax
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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