No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2829 |
4. Check minimum number of eventsNone |
2829 |
5. Include endpointsNone |
2829 |
6. Filter based on genotype QC (FinnGen only) |
2730 |
Control definitions (FinnGen only)
Control exclude
L12_DERMATITISECZEMA
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
L30
Name in latin
Eczema nummulare
Similar endpoints
↥List of similar endpoints to
Nummular dermatitis
based on the number of shared cases.
Similar with more cases:
- Other and unspecified dermatitis
- Dermatitis and eczema
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 24075 | 10311 | 13675 |
| Only index persons | 22125 | 9683 | 12442 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.34 | 0.30 | 0.38 |
| Only index persons | 0.42 | 0.36 | 0.47 |
| Median age at first event (years) | |||
| Whole population | 56.04 | 55.41 | 56.50 |
| Only index persons | 56.05 | 55.42 | 56.55 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2730 | 1237 | 1493 |
| Unadjusted period prevalence (%) | 0.63 | 0.49 | 0.75 |
| Median age at first event (years) | 59.11 | 55.39 | 62.19 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint L12_DERM_NUMMULAR and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_DERM_NUMMULAR | 1.317 [1.19, 1.46] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.135 |
During the follow-up period (1.1.1998 — 31.12.2019), 1496 out of 8851 females with L12_DERM_NUMMULAR died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_DERM_NUMMULAR | 1.417 [1.29, 1.56] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 2670 out of 11649 males with L12_DERM_NUMMULAR died.
Mortality risk
Mortality risk for people of age
years, who have L12_DERM_NUMMULAR.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.113% | 0.221% |
| 5 | 0.597% | 1.576% |
| 10 | 1.655% | 3.876% |
| 15 | 3.315% | 7.247% |
| 20 | 5.847% | 12.554% |
Relationships between endpoints
↥Index endpoint: L12_DERM_NUMMULAR – Nummular dermatitis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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