No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
27026 |
4. Check minimum number of eventsNone |
27026 |
5. Include endpointsNone |
27026 |
6. Filter based on genotype QC (FinnGen only) |
26066 |
Control definitions (FinnGen only)
Control exclude
N14_FEMALEGENNONINF
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF6
Similar endpoints
↥List of similar endpoints to
Menorrhagia
based on the number of shared cases.
Similar with more cases:
- Excessive, frequent and irregular menstruation
- Noninflammatory disorders of female genital tract
- Genitourinary diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 206548 | 206548 | - |
| Only index persons | 186332 | 186332 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 5.92 | 5.92 | - |
| Only index persons | 6.85 | 6.85 | - |
| Median age at first event (years) | |||
| Whole population | - | 44.18 | - |
| Only index persons | - | 43.60 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 26066 | 26066 | - |
| Unadjusted period prevalence (%) | 10.24 | 10.24 | - |
| Median age at first event (years) | 42.79 | 42.79 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint N14_MENORRHAGIA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_MENORRHAGIA | 0.887 [0.81, 0.98] | 0.013 |
| Birth year | 0.999 [0.99, 1.01] | 0.816 |
During the follow-up period (1.1.1998 — 31.12.2019), 2094 out of 77366 females with N14_MENORRHAGIA died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have N14_MENORRHAGIA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.109% | No data |
| 5 | 0.566% | No data |
| 10 | 1.483% | No data |
| 15 | 2.813% | No data |
| 20 | 4.991% | No data |
Relationships between endpoints
↥Index endpoint: N14_MENORRHAGIA – Menorrhagia
GWS hits: 13
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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