No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleonly females |
265735 |
2. Check conditionsNone |
265735 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
15520 |
4. Check minimum number of eventsNone |
15520 |
5. Include endpointsNone |
15520 |
6. Filter based on genotype QC (FinnGen only) |
14864 |
Control definitions (FinnGen only)
Control exclude
O15_PREG_ABORT
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF3
Parent code in ICD-10
O00-O08
Name in latin
Aliae procreationes conceptionis abnormes
Similar endpoints
↥List of similar endpoints to
Other abnormal products of conception
based on the number of shared cases.
Similar with more cases:
- Pregnancy with abortive outcome
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 123450 | 123450 | - |
| Only index persons | 122070 | 122070 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 3.54 | 3.54 | - |
| Only index persons | 4.49 | 4.49 | - |
| Median age at first event (years) | |||
| Whole population | - | 31.31 | - |
| Only index persons | - | 31.30 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 14864 | 14864 | - |
| Unadjusted period prevalence (%) | 5.84 | 5.84 | - |
| Median age at first event (years) | 31.80 | 31.80 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint O15_CONCEPT_ABNORM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_CONCEPT_ABNORM | 0.74 [0.65, 0.84] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.271 |
During the follow-up period (1.1.1998 — 31.12.2019), 719 out of 92630 females with O15_CONCEPT_ABNORM died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_CONCEPT_ABNORM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.056% | No data |
| 5 | 0.406% | No data |
| 10 | 1.098% | No data |
| 15 | 2.209% | No data |
| 20 | 3.967% | No data |
Relationships between endpoints
↥Index endpoint: O15_CONCEPT_ABNORM – Other abnormal products of conception
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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