This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Mental and behavioural disorders due to cocaine
F5_COCAINE
cocaine dependence: A psychologically and socially impaired state, with or without physiological changes, that develops as a result of using cocaine and which leads to compulsive behaviors to acquire the substance.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
50 |
4. Check minimum number of eventsNone |
50 |
5. Include endpointsNone |
50 |
6. Filter based on genotype QC (FinnGen only) |
44 |
Control definitions (FinnGen only)
Control exclude
F5_SUBSNOALCO
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
F10-F19
Name in latin
Perturbationes mentis et modi se gerendi ex usu cocaini
Similar endpoints
↥List of similar endpoints to
Mental and behavioural disorders due to cocaine
based on the number of shared cases.
Similar with more cases:
- Substance use, excluding alcohol
- Substance abuse
- Substance abuse
- Mental and behavioural disorders due to psychoactive substance use
- Any mental disorder
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 540 | 155 | 381 |
| Only index persons | 457 | 137 | 320 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.00 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 30.18 | 29.30 | 30.44 |
| Only index persons | 29.08 | 27.60 | 29.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 44 | 17 | 27 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 30.46 | 27.18 | 32.52 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
Mortality – FinRegistry
↥Association
Association between endpoint F5_COCAINE and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| F5_COCAINE | 5.817 [3.31, 10.22] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 59 out of 271 males with F5_COCAINE died.
Mortality risk
Mortality risk for people of age
years, who have F5_COCAINE.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.888% |
| 5 | No data | 6.195% |
| 10 | No data | 14.98% |
| 15 | No data | 26.713% |
| 20 | No data | 42.334% |
Relationships between endpoints
↥Index endpoint: F5_COCAINE – Mental and behavioural disorders due to cocaine
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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