No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
86 |
4. Check minimum number of eventsNone |
86 |
5. Include endpointsNone |
86 |
6. Filter based on genotype QC (FinnGen only) |
84 |
Control definitions (FinnGen only)
Control exclude
G6_HYDROCEPH
Extra metadata
Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G91
Name in latin
Hydrocephalia posttraumatica non specificata
Similar endpoints
↥List of similar endpoints to
Post-traumatic hydrocephalus, unspecified
based on the number of shared cases.
Similar with more cases:
- Hydrocephalus
- Other neurological diseases
- Neurological diseases
- Neurological diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 825 | 244 | 570 |
| Only index persons | 682 | 217 | 465 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.02 |
| Only index persons | 0.01 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 60.74 | 61.47 | 60.20 |
| Only index persons | 60.24 | 61.26 | 59.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 84 | 25 | 59 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.03 |
| Median age at first event (years) | 66.19 | 62.17 | 67.89 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint G6_HCPOSTRAU and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_HCPOSTRAU | 3.131 [2.25, 4.35] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.551 |
During the follow-up period (1.1.1998 — 31.12.2019), 72 out of 207 females with G6_HCPOSTRAU died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| G6_HCPOSTRAU | 4.172 [3.17, 5.49] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 235 out of 486 males with G6_HCPOSTRAU died.
Mortality risk
Mortality risk for people of age
years, who have G6_HCPOSTRAU.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.262% | 0.89% |
| 5 | 1.526% | 4.357% |
| 10 | 4.536% | 10.32% |
| 15 | 9.383% | 18.425% |
| 20 | 16.445% | 30.377% |
Relationships between endpoints
↥Index endpoint: G6_HCPOSTRAU – Post-traumatic hydrocephalus, unspecified
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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