No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
59 |
4. Check minimum number of eventsNone |
59 |
5. Include endpointsNone |
59 |
6. Filter based on genotype QC (FinnGen only) |
53 |
Control definitions (FinnGen only)
Control exclude
K11_ORAL
Extra metadata
First used in FinnGen datafreeze
DF5
Similar endpoints
↥List of similar endpoints to
Periodontosis
based on the number of shared cases.
Similar with more cases:
- Gingivitis and periodontal diseases
- Diseases of oral cavity, salivary glands and jaws
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 624 | 303 | 307 |
| Only index persons | 534 | 275 | 259 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 50.80 | 48.14 | 53.40 |
| Only index persons | 49.52 | 47.02 | 52.17 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 53 | 29 | 24 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 56.12 | 52.02 | 61.06 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
Mortality – FinRegistry
↥Association
Association between endpoint K11_PERIODONTOSIS and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_PERIODONTOSIS | 2.631 [1.8, 3.85] | < 0.001 |
| Birth year | 0.989 [0.98, 1.0] | 0.072 |
During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 239 males with K11_PERIODONTOSIS died.
Mortality risk
Mortality risk for people of age
years, who have K11_PERIODONTOSIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.494% |
| 5 | No data | 2.946% |
| 10 | No data | 7.188% |
| 15 | No data | 14.082% |
| 20 | No data | 22.837% |
Relationships between endpoints
↥Index endpoint: K11_PERIODONTOSIS – Periodontosis
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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