No definition available.
Disorders of synovium and tendon in diseases classified elsewhere
DOID EFO Endpoint Browser PheWeb
M13_SYNOTENDINOTH
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
473681 |
1. Apply sex-specific ruleNone |
473681 |
2. Check conditionsNone |
473681 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
687 |
4. Check minimum number of eventsNone |
687 |
5. Include endpointsNone |
687 |
6. Filter based on genotype QC (FinnGen only) |
665 |
Control definitions (FinnGen only)
Control exclude
M13_SOFTTISSUE
Extra metadata
Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Similar endpoints
↥List of similar endpoints to
Disorders of synovium and tendon in diseases classified elsewhere
based on the number of shared cases.
Similar with more cases:
- Disorders of synovium and tendon
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5589 | 2480 | 3087 |
| Only index persons | 5300 | 2380 | 2920 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.07 | 0.09 |
| Only index persons | 0.10 | 0.09 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 53.03 | 54.84 | 51.54 |
| Only index persons | 52.30 | 54.19 | 50.77 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 665 | 321 | 344 |
| Unadjusted period prevalence (%) | 0.15 | 0.13 | 0.17 |
| Median age at first event (years) | 53.73 | 54.24 | 53.26 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
Mortality – FinRegistry
↥Association
Association between endpoint M13_SYNOTENDINOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SYNOTENDINOTH | 1.148 [0.98, 1.35] | 0.091 |
| Birth year | 0.994 [0.99, 1.0] | 0.143 |
During the follow-up period (1.1.1998 — 31.12.2019), 339 out of 2095 females with M13_SYNOTENDINOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SYNOTENDINOTH | 1.269 [1.11, 1.45] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 486 out of 2633 males with M13_SYNOTENDINOTH died.
Mortality risk
Mortality risk for people of age
years, who have M13_SYNOTENDINOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.1% | 0.256% |
| 5 | 0.619% | 1.539% |
| 10 | 1.6% | 3.883% |
| 15 | 3.072% | 7.347% |
| 20 | 5.635% | 11.901% |
Relationships between endpoints
↥Index endpoint: M13_SYNOTENDINOTH – Disorders of synovium and tendon in diseases classified elsewhere
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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