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Inflammatory diseases of prostate (prostatitis)

DOID EFO Endpoint Browser PheWeb

N14_PROSTATITIS

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

473681

1. Apply sex-specific rule

only males

207946

2. Check conditions

None

207946

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — N41
  • Hospital discharge: ICD-9 — 601
  • Hospital discharge: ICD-8 — 601
  • Cause of death: ICD-10 — N41
  • Cause of death: ICD-9 — 601
  • Cause of death: ICD-8 — 601

2 out of 7 registries used, show all original rules.

4940

4. Check minimum number of events

None

4940

5. Include endpoints

None

4940

6. Filter based on genotype QC (FinnGen only)

4743

Control definitions (FinnGen only)

Control exclude N14_MALEGEN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 N40-N51
Name in latin Morbi inflammatorii prostatae

Case counts by codes

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FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 38835 - 38835
Only index persons 34992 - 34992
Unadjusted period prevalence (%)
Whole population 1.09 - 1.09
Only index persons 1.34 - 1.34
Median age at first event (years)
Whole population - - 53.19
Only index persons - - 52.12

-FinnGen-

Key figures

All Female Male
Number of individuals 4743 - 4743
Unadjusted period prevalence (%) 2.38 - 2.38
Median age at first event (years) 56.66 - 56.66

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Mortality – FinRegistry

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Association

Association between endpoint N14_PROSTATITIS and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
N14_PROSTATITIS 0.934 [0.86, 1.02] 0.11
Birth year 0.988 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 4219 out of 26579 males with N14_PROSTATITIS died.

Mortality risk

Mortality risk for people of age

years, who have N14_PROSTATITIS.

N-year risk Females Males
1 No data 0.2%
5 No data 1.139%
10 No data 2.711%
15 No data 5.108%
20 No data 8.859%

Relationships between endpoints

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Index endpoint: N14_PROSTATITIS – Inflammatory diseases of prostate (prostatitis)

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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